Research Activities

Dr. Crandall serves on the Executive Committee of the Clinical and Translational Science Institute at Children's National, in partnership with The George Washington University. The CTSI-CN offers unique resources in translating discovery to improved health. It provides highly integrated, cost-effective, investigator-focused resources designed to overcome research barriers, promote collaborative research, and provide research training with a special focus on children’s health. With an emphasis on health disparities and childhood antecedents to adult diseases, CTSI-CN builds upon its pediatric research strengths in areas such as rare diseases, asthma, and neuro-developmental disabilities to collaborate with a national network of 1,200 community health centers.

As an investigator with the District of Columbia Center for AIDS Research, Dr. Crandall studies HIV population dynamics, phylodynamics, the evolution of drug resistance, and gene flow as an indicator of transmission patterns. The mission of the DC CFAR is to expand our multi-institutional effort to support research aimed at ending the HIV epidemic in Washington, DC and beyond in partnership with local government and community.


Dr. Crandall is a principal investigator with the Open Tree of Life, which links all biodiversity through a shared evolutionary history. This project will produce the first online, comprehensive first-draft tree of all 1.8 million named species, accessible to both the public and scientific communities. Assembly of the tree will incorporate previously-published results, with strong collaborations between computational and empirical biologists to develop, test and improve methods of data synthesis. This initial tree of life will not be static; instead, we will develop tools for scientists to update and revise the tree as new data come in. Early release of the tree and tools will motivate data sharing and facilitate ongoing synthesis of knowledge.